Prevalence and clinical characteristics of myelodysplastic syndrome with bone marrow eosinophilia or basophilia.

Prevalence and Clinical Characteristics of Myelodysplastic Syndrome With Bone Marrow Eosinophilia or Basophilia. Short title: Basophilia and Myelodysplastic Syndrome

CLINICAL OBSERVATIONS, INTERVENTIONS, AND THERAPEUTIC TRIALS Prevalence and clinical characteristics of myelodysplastic syndrome with bone marrow eosinophilia or basophilia

By retrospectively analyzing 288 patients with de novo myelodysplastic syndrome (MDS), we sought to determine the prevalence and clinical characteristics of bone marrow eosinophilia and basophilia that were detected at presentation. Bone marrow eosinophilia and basophilia were defined as a differential count of each cell type exceeding 5.0% and 1.0%, respectively. Of 288 patients with MDS, 36 (...

Dysplastic eosinophils in myelodysplastic syndrome: association with complex karyotypes

which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. A 60-year-old woman presented with weakness and a history of multiple blood transfusions in the past 6 months. 9 /L. The peripheral blood smear showed the presence of dysplastic eosinophils (50%) with abnormally large purple-black basophilic granules, hypogr...

How we diagnose and treat WHO-defined systemic mastocytosis in adults.

| 6 | haematologica | 2008; 93(1) Current classification and diagnosis of systemic mastocytosis, and its distinction from other myeloid malignancies associated with bone marrow mastocytosis, remain challenging for both clinicians and hematopathologists. In its upcoming revision, due out in 2008, the World Health Organization (WHO) classification system for myeloid malignancies considers mast ce...

Range Determination of Antigen Expression in Myeloid, Erythroid and Lymphoid Cell Lineages among Patients with Myelodysplastic Syndrome

Background: Myelodysplastic syndrome is a mixed clonal disorder of bone marrow progenitor cells. Understanding the pattern of the different lineage-specific, immature, and mature markers in myelodysplastic syndrome will help in setting-up the frame of reference to diagnose. Patients and Methods: We compared 60 bone marrow samples from 30 newly-diagnosed patients with myelodysplastic syndrome ...